American Cancer Society recommends regular prostate screening for U.S. men, starting at 50
The American Cancer Society on Nov. 12 issued updated guidelines urging regular prostate cancer screening for U.S. men, shifting from an emphasis on individualized decisions to explicit screening recommendations.
According to the American Cancer Society, the update calls for PSA testing every two years for men at average risk ages 50 through 69. The society recommends that Black men begin annual screening at age 45 regardless of family history, and that men who have a father, brother or son diagnosed with prostate cancer also begin screening at 45, with screening frequency to be determined by their family history.
The guidelines say men ages 70 to 74 should discuss with their doctors whether to continue screening. Routine screening is not recommended for men 75 and older, the society said.
Under the updated guidance, a PSA level of 3 ng/mL or higher in men younger than 70 should prompt a repeat test to confirm the result. The society noted there are other explanations for higher PSA levels, including an enlarged prostate, inflammation or infection.
The American Cancer Society reported that when prostate cancer has not spread beyond the prostate or nearby areas, the five-year relative survival rate is nearly 100%. The society estimated more than 333,000 men in the U.S. will be diagnosed in 2026 and about 36,000 will die from the disease.
Dr. Ash Tewari, chair of the Milton and Carroll Petrie Department of Urology at the Icahn School of Medicine at Mount Sinai, told Fox News he has performed more than 10,000 prostate cancer operations and emphasized early detection. “Men think it is going to happen to someone else,” Tewari said in the Fox News article. “We know how to cure 95% of them,” he added.
Tewari and Mount Sinai have deployed mobile prostate cancer screening units to reach more men, the Fox News report said. The first mobile unit, the Mount Sinai Robert F. Smith Mobile Prostate Cancer Screening Unit, began operating in New York City in 2022; another unit was taken to the Atlanta Falcons–Chicago Bears game at Mercedes‑Benz Stadium in Atlanta in October 2026, where the Winship Cancer Institute at Emory University offered free screenings in partnership with the Falcons, the report said.
The Fox News article also noted public outreach efforts tied to the screening push, including a public service announcement directed by actress Brooke Shields and Tewari’s Million Strong Men Initiative, which aims to screen more than one million men.
The society recommends that patients and healthcare providers discuss the potential benefits and harms of screening; for low-risk cancers, the society said close monitoring can be offered as an initial approach.
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